The Lost Apothecary
- Jul 8, 2025
- 2 min read

The Lost Apothecary is a captivating blend of historical fiction and mystery that spans centuries, bringing to life the struggles and resilience of women bound by secrets and the pursuit of justice. Sarah Penner's debut novel intertwines the lives of three women, drawing readers into a dark yet empowering narrative that highlights the timeless challenges faced by women and their enduring strength.
The story begins in 1791 with Nella, an apothecary in London who has turned to dispensing poisons to women seeking retribution against the men who have wronged them. Nella’s life takes an unexpected turn when she meets Eliza, a twelve-year-old sent by her mistress to procure a lethal potion. The friendship that blossoms between Nella and Eliza sets off a chain of events that puts them both in grave danger and threatens to expose the names recorded in Nella’s register—names of women who sought her deadly remedies.
In present-day London, we meet Caroline Parcewell, an aspiring historian grappling with her husband’s infidelity during what was supposed to be their tenth wedding anniversary trip. Caroline stumbles upon an old apothecary vial while mudlarking along the Thames, leading her on a journey of historical discovery that connects her to Nella and Eliza’s world. As Caroline delves deeper, she uncovers the secrets of the apothecary murders and finds a renewed sense of purpose and direction in her own life.
The dual timelines are masterfully woven together, with each chapter alternating between Nella, Eliza, and Caroline’s perspectives. This structure not only maintains the suspense but also highlights the parallels between the lives of women in the 18th century and today. Nella’s transformation from a healer to a dispenser of poisons, driven by betrayal, contrasts with Caroline’s journey of self-discovery and empowerment in the wake of her own betrayal.
Penner’s characters are richly developed, particularly the bond between Nella and Eliza, which evolves into a poignant, almost mother-daughter relationship. Similarly, Caroline’s friendship with Gaynor, a librarian who aids her in her research, provides a contemporary counterpart, emphasising the theme of female solidarity across time.
The novel excels in creating an atmospheric portrayal of historical London, with its dark alleyways and hidden apothecary shop, while also capturing the modern-day thrill of historical investigation. The discovery of the blue vial serves as a symbolic link between the two eras, tying together the threads of mystery and historical intrigue.
While the story delves into themes of betrayal and revenge, it does so with a nuanced approach that avoids glorifying violence. Instead, The Lost Apothecary focuses on the consequences of the characters’ actions and the ways in which they find redemption and strength.
Penner’s writing is both engaging and thought-provoking, making it a book that beckons readers into its world rather than demanding their attention. It’s a journey of intrigue and discovery, filled with suspense and rich historical detail, that ultimately celebrates the resilience and resourcefulness of women.
Overall, The Lost Apothecary is a highly recommended read for those who enjoy historical fiction with a touch of mystery. It’s a beautifully crafted tale that explores the complexities of women’s lives across centuries, leaving readers with a lasting impression of the power of solidarity and the importance of uncovering and honouring the past.




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